BDBM537450 (3-(((1 s,4s)-4-(3-(1-methyl-1H-pyrazol-4-yl)-6-(methylamino)-1H-pyrazolo[4,3-c]pyridin-1-yl)cyclohexyl)oxy)pyridin-2-yl)methanol::US11247990, Example 275

SMILES CNc1cc2n(nc(-c3cnn(C)c3)c2cn1)[C@@H]1CC[C@@H](CC1)Oc1cccnc1CO

InChI Key InChIKey=SUNCVSGYFLTRPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 537450   

TargetTyrosine-protein kinase Mer(Human)
Array Biopharma

US Patent
LigandPNGBDBM537450(US11247990, Example 275 | (3-(((1 s,4s)-4-(3-(1-me...)
Affinity DataIC50: 110nMAssay Description:MER: Compounds of Formula I were screened for their ability to inhibit MER kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Array Biopharma

US Patent
LigandPNGBDBM537450(US11247990, Example 275 | (3-(((1 s,4s)-4-(3-(1-me...)
Affinity DataIC50: 110nMAssay Description:AXL: Compounds of Formula I were screened for their ability to inhibit AXL kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Array Biopharma

US Patent
LigandPNGBDBM537450(US11247990, Example 275 | (3-(((1 s,4s)-4-(3-(1-me...)
Affinity DataIC50: 350nMAssay Description:TYRO3: Compounds of Formula I were screened for their ability to inhibit TYRO3 kinase using Invitrogen's LanthaScreen Eu Kinase Binding technolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent