BDBM537573 4-(6-(ethylamino)-1- ((1s,4s)-4-(2- fluorophenoxy)cyclohexyl)- 1H-pyrazolo[4,3-c]pyridin- 3-yl)-1-methylpyridin- 2(1H)-one::US11247990, Example 398

SMILES CCNc1cc2n(nc(-c3ccn(C)c(=O)c3)c2cn1)C1CC[C@@H](CC1)Oc1ccccc1F

InChI Key InChIKey=IYUFPUXXRXTRRM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 537573   

TargetTyrosine-protein kinase Mer(Human)
Array Biopharma

US Patent
LigandPNGBDBM537573(4-(6-(ethylamino)-1- ((1s,4s)-4-(2- fluorophenoxy)...)
Affinity DataIC50: 20nMAssay Description:MER: Compounds of Formula I were screened for their ability to inhibit MER kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
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TargetTyrosine-protein kinase receptor UFO(Human)
Array Biopharma

US Patent
LigandPNGBDBM537573(4-(6-(ethylamino)-1- ((1s,4s)-4-(2- fluorophenoxy)...)
Affinity DataIC50: 110nMAssay Description:AXL: Compounds of Formula I were screened for their ability to inhibit AXL kinase using Invitrogen's LanthaScreen Eu Kinase Binding technology. H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
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TargetTyrosine-protein kinase receptor TYRO3(Human)
Array Biopharma

US Patent
LigandPNGBDBM537573(4-(6-(ethylamino)-1- ((1s,4s)-4-(2- fluorophenoxy)...)
Affinity DataIC50: 110nMAssay Description:TYRO3: Compounds of Formula I were screened for their ability to inhibit TYRO3 kinase using Invitrogen's LanthaScreen Eu Kinase Binding technolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
Go to US Patent