BDBM537989 US11248006, Compound 2-1-1::US11248006, Compound 2-1-2

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3c(n2)n2-c4cccc(n4)N(CCCCC=CCn2c3=O)C(C)=O)cc1

InChI Key InChIKey=LTXRZDLNNLSWNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 537989   

TargetWee1-like protein kinase(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM537989(US11248006, Compound 2-1-2 | US11248006, Compound ...)
Affinity DataIC50: 62.5nMAssay Description:In the present disclosure, Wee1 enzyme catalysis assay was carried out using the ATP-Glo Max kinase luminescence detection kit (Promega). Kinase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent

TargetWee1-like protein kinase(Human)
Shanghai De Novo Pharmatech

US Patent
LigandPNGBDBM537989(US11248006, Compound 2-1-2 | US11248006, Compound ...)
Affinity DataIC50: 75.2nMAssay Description:In the present disclosure, Wee1 enzyme catalysis assay was carried out using the ATP-Glo Max kinase luminescence detection kit (Promega). Kinase acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2022
Entry Details
US Patent