BDBM539870 2-chloro-4- mercapto- benzonitrile::US11260049, Ex. 8

SMILES Sc1ccc(C#N)c(Cl)c1

InChI Key InChIKey=YPFZXRIMRNJRBE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 539870   

TargetTransient receptor potential cation channel subfamily V member 4(Human)
Glaxosmithkline Intellectual Property (No. 2)

US Patent
LigandChemical structure of BindingDB Monomer ID 539870BDBM539870(2-chloro-4- mercapto- benzonitrile | US11260049, E...)
Affinity DataIC50: 55nMAssay Description:TRPV4 channel activation results in an influx of divalent and monovalent cations including calcium. The resulting changes in intracellular calcium we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent