BDBM540798 US11261211, Compound SB-38

SMILES CC[C@@]1(O)CC[C@H]2[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nnc6ccc(F)cc56)[C@@]4(C)CC[C@H]23)C1

InChI Key InChIKey=RNOYZLHTOHFHGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540798   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM540798(US11261211, Compound SB-38)
Affinity DataIC50: 500nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
US Patent