BDBM540802 US11261211, Compound SB-40

SMILES COC[C@@]1(O)CC[C@H]2[C@@H](CC[C@H]3[C@@H]4CC[C@H](C(=O)Cn5nnc6ccc(F)cc56)[C@@]4(C)CC[C@H]23)C1

InChI Key InChIKey=SPMJMRHOOWMIAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 540802   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Rat)
Sage Therapeutics

US Patent
LigandPNGBDBM540802(US11261211, Compound SB-40)
Affinity DataIC50: 300nMAssay Description:TBPS binding assays using rat brain cortical membranes in the presence of 5 μM GABA has been described (Gee et al, J. Pharmacol. Exp. Ther. 1987...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2022
Entry Details
Go to US Patent