BDBM541936 US11267824, Example 142

SMILES CCC1CCC(CC(O)c2c(sc3cncn23)C2CC2)CC1

InChI Key InChIKey=BLOSNGHZILRUMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 541936   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541936(US11267824, Example 142)
Affinity DataIC50: 85.8nMAssay Description:IDO1: Recombinant full-length human IDO1 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is incubated at a final...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
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TargetTryptophan 2,3-dioxygenase(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM541936(US11267824, Example 142)
Affinity DataIC50: 2.00E+3nMAssay Description:TDO2: Recombinant human TDO comprising amino acids 19-407 with a N-terminal hexahistidine tag expressed in E. coli and purified to homogeneity is inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2022
Entry Details
Go to US Patent