BDBM542160 US11274090, Example 40 Isomer 1

SMILES FC(F)(F)CN1CCN(CC1)c1ccc(NC(=O)[C@@H](NCCc2ccc(cc2)C#N)c2ccccc2)nc1

InChI Key InChIKey=KRUKAYCFGZDZFR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542160   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 542160BDBM542160(US11274090, Example 40 Isomer 1)
Affinity DataIC50: 190nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent