BDBM542217 US11274090, Example 62 Isomer 4

SMILES C[C@H](CN[C@H](C(=O)Nc1ccc(cn1)-n1cc(C)cn1)c1ccccc1)c1ccc(cc1)C#N

InChI Key InChIKey=HSSNGFKFEQUPHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542217   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 542217BDBM542217(US11274090, Example 62 Isomer 4)
Affinity DataIC50: 52.6nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent