BDBM542218 US11274090, Example 63 Isomer 1

SMILES COc1ccc(cc1)[C@H](NCCc1ccc(cc1)C#N)C(=O)Nc1ccc(cn1)-c1cnn(C)c1

InChI Key InChIKey=YQGXKQBJHXKBGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 542218   

TargetHistone acetyltransferase p300(Human)
Constellation Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 542218BDBM542218(US11274090, Example 63 Isomer 1)
Affinity DataIC50: 86nMAssay Description:The full length p300 SPA assay was run following the same protocol as p300 HAT SPA assay, but used 6 nM purified full length p300 (purchased from Act...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2022
Entry Details
US Patent