BDBM54264 4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-1,3-thiazol-2-yl]-1H-pyrrole-2-carboxamide::4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-2-thiazolyl]-1H-pyrrole-2-carboxamide::4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)thiazol-2-yl]-1H-pyrrole-2-carboxamide::4-ethanoyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-1,3-thiazol-2-yl]-1H-pyrrole-2-carboxamide::MLS000375252::SMR000254505::cid_2523404

SMILES CC(=O)c1c(C)[nH]c(C(=O)Nc2nc(cs2)-c2ccc(cc2)-c2ccccc2)c1C

InChI Key InChIKey=GPSAWWSGWSTGLG-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 54264   

TargetNucleotide-binding oligomerization domain-containing protein 1(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54264(4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-1,3-th...)
Affinity DataEC50:  3.76E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetTumor necrosis factor(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54264(4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-1,3-th...)
Affinity DataIC50: 4.41E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetNucleotide-binding oligomerization domain-containing protein 2(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM54264(4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-1,3-th...)
Affinity DataIC50: 4.86E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM54264(4-acetyl-3,5-dimethyl-N-[4-(4-phenylphenyl)-1,3-th...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay