BDBM546668 US11292781, Compound T152

SMILES C[C@@H]1[C@H]2CCc3c(nc(nc3[C@]2(C)C=C(C#N)C1=O)-c1ccnc(CCC(=O)N(C)C)c1)-c1ccccc1F

InChI Key InChIKey=VIJATIPTIFOHHR-IEEYFSLBSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 546668   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Reata Pharmaceuticals

US Patent
LigandPNGBDBM546668(US11292781, Compound T152)
Affinity DataIC50:  81nMAssay Description:The RORγ assay system was purchased from Indigo Biosciences. This nuclear receptor assay utilizes a human cell line that has been engineered to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent