BDBM546776 (1S,4R)-4-[(7S)-2-benzyl-6-(methoxycarbonyl)-7-methyl-3H,6H,7H,8H,9H-imidazo[4,5-f]quinolin-3-yl]-2,2-dimethylcyclohexane-1-carboxylic Acid::US11292791, Example 49

SMILES COC(=O)[C@H]1CC[C@H](CC1(C)C)n1c(Cc2ccccc2)nc2c3CC[C@H](C)N(C(=O)OC)c3ccc12

InChI Key InChIKey=OWGKXOROGYEVCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 546776   

TargetCREB-binding protein(Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 546776BDBM546776((1S,4R)-4-[(7S)-2-benzyl-6-(methoxycarbonyl)-7-met...)
Affinity DataIC50: 550nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Forma Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 546776BDBM546776((1S,4R)-4-[(7S)-2-benzyl-6-(methoxycarbonyl)-7-met...)
Affinity DataIC50: 5.05E+4nMAssay Description:The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent