BDBM547710 US11292792, CMPD # I-40

SMILES CC(C)(C)OC(=O)N1CCc2c(C1)c1cccnc1n2C1CCC(=O)NC1=O

InChI Key InChIKey=XKXMVIZLUBDOHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547710   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 547710BDBM547710(US11292792, CMPD # I-40)
Affinity DataIC50: 20nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent