BDBM547711 US11292792, CMPD # I-41

SMILES O=C1CCC(N2c3ccccc3C(=NCC2=O)c2ccccc2)C(=O)N1

InChI Key InChIKey=ZEKJFFGYWAEQSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 547711   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Kymera Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 547711BDBM547711(US11292792, CMPD # I-41)
Affinity DataIC50: 65nMAssay Description:Equal volumes of His-tagged CRBN-DDB1 complex (56 nM) was mixed with Eu-cryptate labeled Anti-6HIS-monoclonal antibody (50× dilution from the commerc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2022
Entry Details
US Patent