BDBM549391 US11304929, Example 01-028::ethyl 2-{4-[(1S)-1-[(4,5-difluoro-1,6-dimethyl-1H-indol-2-yl)formamido]-2- hydroxyethyl]benzenesulfonyl}acetate

SMILES CCOC(=O)CS(=O)(=O)c1ccc(cc1)[C@@H](CO)NC(=O)c1cc2c(F)c(F)c(C)cc2n1C

InChI Key InChIKey=VZDADGTXKYIEDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549391   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 549391BDBM549391(ethyl 2-{4-[(1S)-1-[(4,5-difluoro-1,6-dimethyl-1H-...)
Affinity DataIC50: 267nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 549391BDBM549391(ethyl 2-{4-[(1S)-1-[(4,5-difluoro-1,6-dimethyl-1H-...)
Affinity DataIC50: 525nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
US Patent