BDBM549454 US11304929, Example 01-013::methyl 2-{4-[(1S)-1-[(4-chloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2- hydroxyethyl]benzenesulfonyl}acetate

SMILES COC(=O)CS(=O)(=O)c1ccc(cc1)[C@@H](CO)NC(=O)c1cc2c(Cl)cc(C)cc2n1C

InChI Key InChIKey=FRRVTYANBMUOQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 549454   

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM549454(methyl 2-{4-[(1S)-1-[(4-chloro-1,6-dimethyl-1H-ind...)
Affinity DataIC50: 87nMAssay Description:Compounds are dispensed onto assay plates (black, low volume, flat bottom 384 well, Corning) using an Access Labcyte Workstation with the Labcyte Ech...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2022
Entry Details
Go to US Patent

TargetD-3-phosphoglycerate dehydrogenase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM549454(methyl 2-{4-[(1S)-1-[(4-chloro-1,6-dimethyl-1H-ind...)
Affinity DataIC50: 162nMAssay Description:Inhibition of PHGDH (unknown origin) preincubated for 30 mins followed by substrate addition and measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed