BDBM550527 US11311528, Ex. 1-1::US11311528, Ex. 1-2

SMILES CC(C)(C)c1ccc(cc1Cl)N1[C@H]([C@H](C(O)=O)c2ccccc2C1=O)c1ccc2OCCOc2c1

InChI Key InChIKey=XGDKZTMGSABEJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 550527   

LigandPNGBDBM550527(US11311528, Ex. 1-2 | US11311528, Ex. 1-1)
Affinity DataIC50: 33nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

LigandPNGBDBM550527(US11311528, Ex. 1-2 | US11311528, Ex. 1-1)
Affinity DataIC50: 53nMAssay Description:The ability of compounds to bind STING is quantified by their ability to compete with tritiated cGAMP ligand for human STING receptor membrane using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent