BDBM550800 8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-(5-methylfuran-2-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine 8::US11312705, Example 8

SMILES Cc1ccc(o1)-c1nc(N)n2cnnc2c1-c1cc(C)nc(c1)C(F)(F)F

InChI Key InChIKey=LAAQYGIJDAHUTM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 550800   

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550800(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-(5-...)
Affinity DataIC50: 0.180nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550800(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-(5-...)
Affinity DataIC50: 0.180nMAssay Description:CHO-K1/A2aR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 800 μg/ml bleomycin. The cells were digested with the c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM550800(8-(2-Methyl-6-(trifluoromethyl)pyridin-4-yl)-7-(5-...)
Affinity DataIC50: 203nMAssay Description:CHO-K1/A2bR cells were cultured in DMEM/F12 medium containing 10% fetal bovine serum and 1 mg/ml G418. The cells were digested with the cell separati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
Go to US Patent