BDBM550828 2-{5-(Benzyloxy)-3-[(methylamino)methyl]-1H-pyrazol-1-yl}-2-cyclohexyl-ethanol Hydrochloride::US11312688, Example 328

SMILES CNCc1cc(OCc2ccccc2)n(n1)C(CO)C1CCCCC1

InChI Key InChIKey=BTRKQXZGXAWSKD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 550828   

TargetSodium-dependent serotonin transporter(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM550828(2-{5-(Benzyloxy)-3-[(methylamino)methyl]-1H-pyrazo...)
Affinity DataKi:  3.60nMAssay Description:The [3H] citalopram binding was measured according to the method disclosed in Owens M. J. et al., J. Pharm. Exp. Ther., 283, 1305-1322 (1997). In spe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM550828(2-{5-(Benzyloxy)-3-[(methylamino)methyl]-1H-pyrazo...)
Affinity DataKi:  193nMAssay Description:A solution of 200 μL in total was prepared by mixing 50 μL of [3H] mesulergine (manufactured by GE Healthcare) diluted with 50 mmol/L Tris-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent