BDBM551158 5-[2,5-Bis(trifluoromethyl)imidazo[4,5-b]pyridin-3-yl]-7-methyl-indolin-2-one;::US11312712, Example 275

SMILES Cc1cc(cc2CC(=O)Nc12)-n1c(nc2ccc(nc12)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LGFFFCXCEMFJDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 551158   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM551158(5-[2,5-Bis(trifluoromethyl)imidazo[4,5-b]pyridin-3...)
Affinity DataIC50: 0.126nMAssay Description:An in vitro assay was used to determine the potency of test compounds as inhibitors of the glutamate response of the channel formed by GluA1o-γ8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent