BDBM551881 (3-amino-6-(methylsulfonyl)-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-2-yl)(2,2-dimethyl-1,2,3,4-tetrahydroquinolin-4-yl)methanone::US11312723, Example 39

SMILES CC1(C)CC(C(=O)n2nc3CN(CCc3c2N)S(C)(=O)=O)c2ccccc2N1

InChI Key InChIKey=SHZCWYZJVONKFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551881   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551881BDBM551881((3-amino-6-(methylsulfonyl)-4,5,6,7-tetrahydropyra...)
Affinity DataIC50: 150nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetProthrombin(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551881BDBM551881((3-amino-6-(methylsulfonyl)-4,5,6,7-tetrahydropyra...)
Affinity DataIC50: 4.50E+4nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent