BDBM551955 3-amino-N,N- dimethyl-2- (1,2,3,4- tetrahydro- quinoline-4- carbonyl)- 4,5-dihydro-2H- pyrazolo[3,4- c]pyridine- 6(7H)- carboxamide::US11312723, Example 123

SMILES CN(C)C(=O)N1CCc2c(C1)nn(C(=O)C1CCNc3ccccc13)c2N

InChI Key InChIKey=ADNOHCXGLXWXPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 551955   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551955BDBM551955(3-amino-N,N- dimethyl-2- (1,2,3,4- tetrahydro- qui...)
Affinity DataIC50: 350nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetProthrombin(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 551955BDBM551955(3-amino-N,N- dimethyl-2- (1,2,3,4- tetrahydro- qui...)
Affinity DataIC50: 8.00E+4nMAssay Description:Thrombin. In a 96-well white opaque plate, 80 μl of assay buffer was added to each well. Test compounds were added, and serially diluted as abov...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent