BDBM552011 (3-amino-6- (cyclobutyl- sulfonyl)-4,5,6,7- tetrahydro- pyrazolo[3,4- cjpyridin-1- yl)(8-methyl- 1,2,3,4- tetrahydro- quinolin-4- yl)methanone::US11312723, Example 184

SMILES Cc1cccc2C(CCNc12)C(=O)n1nc(N)c2CCN(Cc12)S(=O)(=O)C1CCC1

InChI Key InChIKey=LIAWKYWPOZAOBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552011   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 552011BDBM552011((3-amino-6- (cyclobutyl- sulfonyl)-4,5,6,7- tetrah...)
Affinity DataIC50: 1.10E+4nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent