BDBM552016 (3-amino-6,7- dihydropyrano[4, 3-c]pyrazol- 1(4H)-yl)(8- methyl-1,2,3,4- tetrahydro- quinolin-4- yl)methanone::US11312723, Example 189

SMILES Cc1cccc2C(CCNc12)C(=O)n1nc(N)c2COCCc12

InChI Key InChIKey=FKNXUEYRMURPLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552016   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 552016BDBM552016((3-amino-6,7- dihydropyrano[4, 3-c]pyrazol- 1(4H)-...)
Affinity DataIC50: 4.00E+4nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent