BDBM552022 (R*)-(3-amino- 4,5- dihydropyrano[3, 4-c]pyrazol- 2(7H)-yl)(6- fluoro-1,2,3,4- tetrahydro- quinolin-4- yl)methanone::US11312723, Example 197

SMILES Nc1c2CCOCc2nn1C(=O)[C@@H]1CCNc2ccc(F)cc12

InChI Key InChIKey=AOEYMISDWDSSAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552022   

TargetCoagulation factor XII(Human)
Rockefeller University

US Patent
LigandChemical structure of BindingDB Monomer ID 552022BDBM552022((R*)-(3-amino- 4,5- dihydropyrano[3, 4-c]pyrazol- ...)
Affinity DataIC50: 4.00E+4nMAssay Description:In a 96-well clear bottom plate, 80 μl of assay buffer was added to each well. Assay buffer consists of 0.5× Hank's Balanced Salt Solution (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent