BDBM553046 N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2-[rac-(3R)-3,4- dimethylpiperazin-1- yl]phenyl]-3- (trifluoromethyl)-1H- pyrazole-4-carboxamide::US11319299, Example 96

SMILES C[C@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2c[nH]nc2C(F)(F)F)CCN1C

InChI Key InChIKey=RBCIHUVQKPTWLN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553046   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553046BDBM553046(N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...)
Affinity DataKd:  7.71nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent