BDBM553214 N-[5-(6-cyano-4- methylpyridin-3-yl)-4- fluoro-2-[rac-(3R,5S)- 3,4,5-trimethylpiperazin- 1-yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 269

SMILES Cc1cc(C#N)ncc1-c1cc(NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)c(N2C[C@@H](C)N(C)[C@@H](C)C2)cc1F

InChI Key InChIKey=PDQNPSGFIRDJOP-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553214   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553214BDBM553214(N-[5-(6-cyano-4- methylpyridin-3-yl)-4- fluoro-2-[...)
Affinity DataKd:  8.74nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent