BDBM553223 N-[4-fluoro-5-[2-(4- methylpiperazin-1-yl) pyrimidin-5-yl]-2-[rac- (3R)-3,4-dimethylpiperazin-1- yl]phenyl]-1-methyl-6-oxo-4- (trifluoromethyl)pyridine- 3-carboxamide::US11319299, Example 279

SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1cn(C)c(=O)cc1C(F)(F)F)-c1cnc(nc1)N1CCN(C)CC1

InChI Key InChIKey=DQTHXSJKHKMLNF-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553223   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553223BDBM553223(N-[4-fluoro-5-[2-(4- methylpiperazin-1-yl) pyrimid...)
Affinity DataKd:  2.08nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent