BDBM553225 N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2-[rac-(3R,5S)-3,4,5- trimethylpiperazin-1-yl]phenyl]- 3-hydroxybenzamide::US11319299, Example 281

SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1cccc(O)c1)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=BBSKAFJIOXPDNK-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553225   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553225BDBM553225(N-[4-fluoro-5-(2- morpholin-4-ylpyrimidin- 5-yl)-2...)
Affinity DataKd:  29.1nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent