BDBM553242 4-fluoro-N-[4-fluoro-5- (2-morpholin-4-ylpyrimidin- 5-yl)-2-[rac-(3R)-3,4- dimethylpiperazin-1- yl]phenyl]-2- (trifluoromethyl)benzamide::US11319299, Example 298::US11319299, Example 299

SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1ccc(F)cc1C(F)(F)F)-c1cnc(nc1)N1CCOCC1

InChI Key InChIKey=RYOBVJGRASCNFQ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 553242   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM553242(US11319299, Example 298 | 4-fluoro-N-[4-fluoro-5- ...)
Affinity DataKd:  4.22nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandPNGBDBM553242(US11319299, Example 298 | 4-fluoro-N-[4-fluoro-5- ...)
Affinity DataKd:  0.569nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent