BDBM553277 N-[4-fluoro-5-(2-morpholin-4- ylpyrimidin-5-yl)-2-[rac- (3R,4R)-3-[ethyl(methyl) amino]-4-fluoropyrrolidin-1- yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 344

SMILES CCN(C)[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCOCC4)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H]1F

InChI Key InChIKey=NBCIAIRPLBKECO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553277   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553277BDBM553277(N-[4-fluoro-5-(2-morpholin-4- ylpyrimidin-5-yl)-2-...)
Affinity DataKd:  12.4nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent