BDBM553282 N-[5-[2-(2,2-dimethylmorpholin- 4-yl)pyrimidin-5-yl]-4- fluoro-2-[rac-(3R,5S)- 3,4,5-trimethylpiperazin- 1-yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 350

SMILES C[C@@H]1CN(c2cc(F)c(-c3cnc(N4CCOC(C)(C)C4)nc3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C

InChI Key InChIKey=RUPXPESJMQELMN-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553282   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553282BDBM553282(N-[5-[2-(2,2-dimethylmorpholin- 4-yl)pyrimidin-5-y...)
Affinity DataKd:  1.42nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent