BDBM553305 4-fluoro-N-[4-fluoro-5- [2-(4-methylpiperazin-1- yl)pyrimidin-5-yl]-2-[rac- (3R,5S)-3,4,5-trimethylpiperazin- 1-yl]phenyl]-2-(trifluoromethyl) benzamide::US11319299, Example 379

SMILES C[C@H]1CN(C[C@@H](C)N1C)c1cc(F)c(cc1NC(=O)c1ccc(F)cc1C(F)(F)F)-c1cnc(nc1)N1CCN(C)CC1

InChI Key InChIKey=GWAUIRJYZIWNHS-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553305   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553305BDBM553305(4-fluoro-N-[4-fluoro-5- [2-(4-methylpiperazin-1- y...)
Affinity DataKd:  0.933nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent