BDBM553326 4-fluoro-N-[4-fluoro-5-[2- (4-methyl-1,4-diazepan-1- yl)pyrimidin-5-yl]-2-[rac- (3R)-3,4-dimethylpiperazin-1- yl]phenyl]-2-(trifluoromethyl) benzamide::US11319299, Example 400

SMILES C[C@H]1CN(CCN1C)c1cc(F)c(cc1NC(=O)c1ccc(F)cc1C(F)(F)F)-c1cnc(nc1)N1CCCN(C)CC1

InChI Key InChIKey=DBNDJZSXBHLXAG-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553326   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553326BDBM553326(4-fluoro-N-[4-fluoro-5-[2- (4-methyl-1,4-diazepan-...)
Affinity DataKd:  1.47nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent