BDBM553363 N-[4-fluoro-5-[1-(6- methoxypyrimidin-4-yl)- 2,5-dihydropyrrol-3-yl]-2-[rac- (3R,5S)-3,4,5- trimethylpiperazin- 1-yl]phenyl]-6-oxo-4- (trifluoromethyl)-1H- pyridine-3-carboxamide::US11319299, Example 438

SMILES COc1cc(N2CC=C(c3cc(NC(=O)c4c[nH]c(=O)cc4C(F)(F)F)c(N4C[C@@H](C)N(C)[C@@H](C)C4)cc3F)C2)ncn1

InChI Key InChIKey=PQUHWGWCJFCTHD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553363   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553363BDBM553363(N-[4-fluoro-5-[1-(6- methoxypyrimidin-4-yl)- 2,5-d...)
Affinity DataKd:  1.99nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent