BDBM553521 4-(difluoromethyl)-N-[4- fluoro-5-[4-fluoro-3- (methylcarbamoyl)phenyl]- 2-[rac-(3R,5S)-3,4,5- trimethylpiperazin-1- yl]phenyl]-6-oxo-1H- pyridine-3-carboxamide::US11319299, Example 606

SMILES CNC(=O)c1cc(-c2cc(NC(=O)c3c[nH]c(=O)cc3C(F)F)c(N3C[C@@H](C)N(C)[C@@H](C)C3)cc2F)ccc1F

InChI Key InChIKey=HJHHREHZGGOJQD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553521   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553521BDBM553521(4-(difluoromethyl)-N-[4- fluoro-5-[4-fluoro-3- (me...)
Affinity DataKd:  1.86nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent