BDBM553526 4-fluoro-N-[4-fluoro-5- [2-[rac-(2R)-2- methylmorpholin-4- yl]pyrimidin-5-yl]-2-[rac- (3S,5R)-3,4,5- trimethylpiperazin-1- yl]phenyl]-3,5- dimethylbenzamide::US11319299, Example 611

SMILES C[C@H]1CN(CCO1)c1ncc(cn1)-c1cc(NC(=O)c2cc(C)c(F)c(C)c2)c(cc1F)N1C[C@H](C)N(C)[C@H](C)C1

InChI Key InChIKey=GTTCDOFHAWTLKM-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553526   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553526BDBM553526(4-fluoro-N-[4-fluoro-5- [2-[rac-(2R)-2- methylmorp...)
Affinity DataKd:  1.55nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent