BDBM553559 4-(difluoromethyl)-N-[4- fluoro-5-[1-(5- methoxypyrimidin-2-yl)- 3,6-dihydro-2H-pyridin- 5-yl]-2-[rac-(3R,5S)- 3,4,5-trimethylpiperazin- 1-yl]phenyl]-6-oxo-1H- pyridine-3-carboxamide::US11319299, Example 645

SMILES COc1cnc(N2CCC=C(c3cc(NC(=O)c4c[nH]c(=O)cc4C(F)F)c(N4C[C@@H](C)N(C)[C@@H](C)C4)cc3F)C2)nc1

InChI Key InChIKey=MIHGFIYHNJAJKO-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553559   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553559BDBM553559(4-(difluoromethyl)-N-[4- fluoro-5-[1-(5- methoxypy...)
Affinity DataKd:  1.41nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent