BDBM553601 N-[5-[1-(5-cyano-1,3- thiazol-2-yl)-3,6-dihydro- 2H-pyridin-5-yl]-4- fluoro-2-[rac-(3R)-3,4- dimethylpiperazin-1- yl]phenyl]-4- (difluoromethyl)-6-oxo- 1H-pyridine-3- carboxamide::US11319299, Example 688

SMILES C[C@H]1CN(c2cc(F)c(C3=CCCN(c4ncc(C#N)s4)C3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)F)CCN1C

InChI Key InChIKey=RLQIXTSKXXDHGE-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553601   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553601BDBM553601(N-[5-[1-(5-cyano-1,3- thiazol-2-yl)-3,6-dihydro- 2...)
Affinity DataKd:  2.49nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent