BDBM553618 (3,3-difluorocyclobutyl) 5-[2-fluoro-5-[[4-fluoro- 2-(trifluoromethyl)benzoyl] amino]-4-[rac-(3R)-3,4- dimethylpiperazin-1- yl]phenyl]-3,6-dihydro- 2H-pyridine-1-carboxylate::US11319299, Example 706

SMILES C[C@H]1CN(c2cc(F)c(C3=CCCN(C(=O)OC4CC(F)(F)C4)C3)cc2NC(=O)c2ccc(F)cc2C(F)(F)F)CCN1C

InChI Key InChIKey=HAOYBNIUIBWCFJ-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553618   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553618BDBM553618((3,3-difluorocyclobutyl) 5-[2-fluoro-5-[[4-fluoro-...)
Affinity DataKd:  3.81nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent