BDBM553666 6-oxo-N-(3',5',6-trifluoro- 4'-(((R)-tetrahydrofuran- 3-yl)carbamoyl)-4- ((3S,5R)-3,4,5- trimethylpiperazin-1-yl)- [1,1'-biphenyl]-3-yl)-4- (trifluoromethyl)-1,6- dihydropyridine-3- carboxamide::US11319299, Example 762

SMILES C[C@@H]1CN(c2cc(F)c(-c3cc(F)c(C(=O)N[C@@H]4CCOC4)c(F)c3)cc2NC(=O)c2c[nH]c(=O)cc2C(F)(F)F)C[C@H](C)N1C

InChI Key InChIKey=DCXUVEFLYACNAD-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 553666   

TargetWD repeat-containing protein 5(Human)
Propellon Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 553666BDBM553666(6-oxo-N-(3',5',6-trifluoro- 4'-(((R)-tetrahydrofur...)
Affinity DataKd:  0.900nMAssay Description:Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o...More data for this Ligand-Target Pair
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Date in BDB:
8/7/2022
Entry Details
US Patent