BDBM554239 ((R)-2-(((2R,3S,4R,5R)-5-(6-chloro-4- (cyclopentylamino)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)-3,4- dihydroxytetrahydrofuran-2-yl)methoxy)-1- hydroxy-3-(2H-tetrazol-5-yl)propan-2- yl)phosphonic acid::US11325938, Ex 104

SMILES c1c2c(nc(nc2n(n1)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[C@@](Cc4n[nH]nn4)(CO)P(=O)(O)O)O)O)Cl)NC5CCCC5

InChI Key InChIKey=PVVWULAPDGYSNQ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 554239   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 554239BDBM554239(US11325938, Ex 104 | ((R)-2-(((2R,3S,4R,5R)-5-(6-c...)
Affinity DataIC50: 100nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 25 mM Tris-HCL, pH 7.4, 0.01%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2022
Entry Details
US Patent
PDB3D3D Structure (crystal)