BDBM555424 US11344549, Example 100

SMILES CCn1cc(Nc2ncc(C(N)=O)c(NCCc3ccc(F)cc3)n2)cn1

InChI Key InChIKey=BUDVVHKCXYBYFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 555424   

TargetTyrosine-protein kinase JAK3(Human)
Beijing Scitech Mq Pharmaceuticals

US Patent
LigandPNGBDBM555424(US11344549, Example 100)
Affinity DataIC50: 3.16nMAssay Description:JAK3 (the final concentration was 0.36 nM); ATP (the final concentration was 10 μM); ULight-labeled JAK-1 (Tyr1023) Peptide (the final concentra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent