BDBM557217 5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-yl)- N-(tetrahydro-2H- pyran-4-yl)-1H-::US11352340, Example 269

SMILES Cc1[nH]c(nc1C(=O)NC1CCOCC1)-c1cc(ccn1)-c1cncc(c1)N1CCOCC1

InChI Key InChIKey=FOQSZHAKPICEPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 557217   

LigandPNGBDBM557217(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

LigandPNGBDBM557217(5-Methyl-2-(5- morpholin-4-yl-3, 4'-bipyridin-2'-y...)
Affinity DataIC50: 50nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent