BDBM558441 2,2-Difluoro-1-[4-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]oxymethyl]phenyl]ethanol::US11365192, Example 59-2

SMILES OC(Cc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1)C(F)F

InChI Key InChIKey=XCDDYPDNFKSDSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558441   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558441(US11365192, Example 59-2 | 2,2-Difluoro-1-[4-[[6-(...)
Affinity DataIC50: 100nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558441(US11365192, Example 59-2 | 2,2-Difluoro-1-[4-[[6-(...)
Affinity DataIC50: 1.80E+3nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent