BDBM558764 1-((6-Acetylpyridin-3-yl)methyl)-3-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-::US11365205, Example 32

SMILES CC(=O)c1ccc(CN2CCN(CC(O)CN3CCc4ccccc4C3)C2=O)cn1

InChI Key InChIKey=ZNDSHNMQEMMNMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558764   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 558764BDBM558764(1-((6-Acetylpyridin-3-yl)methyl)-3-(3-(3,4-dihydro...)
Affinity DataIC50: 2.10E+3nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent