BDBM558839 R)-5-(4-acetylpiperazine-1-carbonyl)-6-((3-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-::US11365205, Example 103

SMILES CC(=O)N1CCN(CC1)C(=O)c1cc(cnc1CN1CCN(C[C@H](O)CN2CCc3ccccc3C2)C1=O)C#N

InChI Key InChIKey=DKGPCESYTFDYAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 558839   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandChemical structure of BindingDB Monomer ID 558839BDBM558839(R)-5-(4-acetylpiperazine-1-carbonyl)-6-((3-(3-(3,4...)
Affinity DataIC50: 5.46E+3nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent