BDBM562651 Methyl 2-(4-((2-cyclopentyl-6-ethylpyrimidin-4-yl)methyl)phenyl)acetate::US11401286, Example 223

SMILES CCc1cc(Cc2ccc(CC(=O)OC)cc2)nc(n1)C1CCCC1

InChI Key InChIKey=ZPXJKISBDCYVAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562651   

TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Tetra Discovery Partners

US Patent
LigandChemical structure of BindingDB Monomer ID 562651BDBM562651(US11401286, Example 223 | Methyl 2-(4-((2-cyclopen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Human)
Tetra Discovery Partners

US Patent
LigandChemical structure of BindingDB Monomer ID 562651BDBM562651(US11401286, Example 223 | Methyl 2-(4-((2-cyclopen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
US Patent