BDBM562835 2-((2S,5R,6S)-6-(3-Chlorophenyl)-5-(4-chlorophenyl)-4-(cyclopropylmethyl)-5-methyl-3-oxomorpholin-2-yl)acetic acid::US11407721, Example 82

SMILES C[C@]1([C@@H](O[C@@H](CC(O)=O)C(=O)N1CC1CC1)c1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key InChIKey=KSWKEATWRRWERE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562835   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 562835BDBM562835(US11407721, Example 82 | 2-((2S,5R,6S)-6-(3-Chloro...)
Affinity DataIC50: 6.26E+3nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
US Patent